Anastrozole is an aromatase inhibitor used in hormone replacement therapy for men to manage and prevent the conversion of testosterone into estrogen. This medication helps maintain optimal testosterone levels while reducing estrogen levels, which can be beneficial for men undergoing testosterone replacement therapy (TRT). By lowering estrogen, anastrozole can prevent side effects such as gynecomastia (enlarged breast tissue), water retention, and mood swings. Administered orally, it is particularly useful for men experiencing elevated estrogen levels during TRT, promoting a balanced hormonal environment and enhancing overall well-being.